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Acta Médica Peruana

On-line version ISSN 1728-5917


ROMERO YAURI, José; CASTILLO, Alejandro  and  CASTILLO-SOTO, Ana. Cranial base chondrosarcoma: Clinicopathological analysis of a case. Acta méd. Peru [online]. 2021, vol.38, n.3, pp.226-229. ISSN 1728-5917.


Chondrosarcoma is an unusual malignant neoplasm; cranial location is rare. Sometimes its complete resection is not possible because of vicinity of the mass to important vascular and neural structures.

Clinical case:

This is a 56-year old female subject who developed headache in the right side, paresthesia in the right side of her upper lip, short term memory loss, and ageusia. A magnetic resonance imaging study showed an enhanced extra-axial mass. This patient underwent complete surgical resection. The anatomopathological study showed a well differentiated chondrosarcoma of the cranial base.


Chondrosarcoma is a malignancy with pure differentiation of the hyaline cartilage. It represents 0.15% of all intracranial tumors, and this is the second case with a cranial base location reported in Peru. Both histological characteristics and immunohistochemistry markers revealed the classic characteristics of this tumor. Therapy is given on an individualized basis.

Keywords : Cranial base neoplasms; Chondrosarcoma; Immunohistochemistry.

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